Dr. William (Tripp) C. Griffin, III
Research Assistant Professor, Department of Psychiatry and Behavioral Sciences |
Research Interests Dr. Griffin's research interests broadly include understanding the neurobiological adaptations in the brain that may underlie the urge to drink and the maintenance of alcohol drinking. Areas of active investigation consist of examining the glutamatergic, cholinergic and neuropeptide (CRF) signaling systems in brain regions that regulate alcohol consumption. An emerging area of Dr. Griffin's research is examining the interactive effects of alcohol with methylphenidate (Ritalin) on behavior and various neurotransmitter systems in forebrain areas.
Education | University of North Carolina, Chapel Hill, NC | B.S. | 1993 | Biology | | University of North Carolina, Chapel Hill, NC | B.S. | 1996 | Pharmacy | | SE Regional Medical Center, Lumberton, NC | Residency | 1997 | Pharmacy | | West Virginia University, Morgantown, WV | Ph.D. | 2001 | Pharmacology | | Medical University of South Carolina, Charleston, SC | Postdoctoral | 2008 | Addiction Biology |
Professional Experience | 1996-1997 | ASHP Pharmacy Practice Resident, Southeastern Regional Medical Center, Lumberton, NC | | 1997-2001 | Graduate Research Assistant, Department of Pharmacology and Toxicology, West Virginia University School of Medicine, Morgantown, WV | | 2001-2005 | Post-Doctoral Fellow, Center for Drug and Alcohol Programs, Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC | | 2006-2008 | Post-Doctoral Fellow, Charleston Alcohol Research Center, Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC | | 2008-present | Research Assistant Professor, Center for Drug and Alcohol Problems, Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC |
Awards and Honors
| 1992-1996 | University of North Carolina Dean’s List | | 1994 | Summer Research Assistantship, Cancer Education Program, UNC Hospitals | | 1999-2000 | WVU School of Medicine (SoM) Graduate Stipend | | 1999-2001 | West Virginia University (WVU) Doctoral Student Travel Awards | 1999-
present | Member, Society for Neuroscience | | 2000 | International Behavioral Neuroscience Society Travel Award | | 2000 | WVU SoM Academic Achievement Award (Highest GPA) | | 2005 | Research Society on Alcoholism Junior Investigator Award | 2005-
present | Member, Research Society on Alcoholism |
Certifications | 1996-present | NC Registered Pharmacist License #13482 | | 2002-present | SC Registered Pharmacist License #010599 |
Recent Publications Bell GH, Griffin WC, 3rd & Patrick KS. Oral and transdermal dl-methylphenidate-ethanol interactions in C57BL/6J mice: Potentiation of locomotor activity with oral delivery. Pharmacology, Biochemistry, and Behavior 100(2):264-270, 2011. PMCID: 3199322 Bell GH, Novak AJ, Griffin WC, 3rd & Patrick KS. Transdermal and oral dl-methylphenidate-ethanol interactions in C57BL/6J mice: Transesterification to ethylphenidate and elevation of d-methylphenidate concentrations. Journal of Pharmaceutical Sciences 100(7):2966-2978, 2011. Carrara-Nascimento PF, Griffin WC, 3rd, Pastrello DM, Olive MF & Camarini R. Changes in extracellular levels of glutamate in the nucleus accumbens after ethanol-induced behavioral sensitization in adolescent and adult mice. Alcohol 45(5):451-460, 2011. McGovern RW, Middaugh LD, Patrick KS & Griffin WC, 3rd. The discriminative stimulus properties of methylphenidate in C57BL/6J mice. Behavioural Pharmacology 22(1):14-22, 2011. PMCID: 3099148 Griffin WC, 3rd, Nguyen SA, Deleon CP & Middaugh LD. Effects of vigabatrin, an irreversible GABA transaminase inhibitor, on ethanol reinforcement and ethanol discriminative stimuli in mice. Behavioural Pharmacology 23(2):178-190, 2012. PMCID: 3296837 Lopez MF, Griffin WC, 3rd, Melendez RI & Becker HC. Repeated cycles of chronic intermittent ethanol exposure leads to the development of tolerance to aversive effects of ethanol in C57BL/6J mice. Alcoholism: Clinical & Experimental Research 36(7):1180-1187, 2012.
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