Dr. Jacqueline F. McGinty
Professor, Department of Neurosciences
Professor, Department of Psychiatry and Behavioral Sciences
Associate Dean, College of Graduate Studies |
Research Interests Dr. McGinty’s research focuses on the effects of drugs of abuse on neurotransmitter release and gene expression in the rat brain and the effects of methamphetamine neurotoxicity in neurotrophic factor knockout mice during aging. Currently Dr. McGinty is using cDNA microarray technology, in situ hybridization, immunoblotting, and immunohistochemistry to characterize changes in gene expression that may signify longterm neuroadaptations in the brain thought to underlie drug and alcohol addiction and neurotoxicity during aging. Education | Connecticut College, New London, CT | B.A. | 1972 | Psychology | | Downstate Medical Center SUNY, Brooklyn, NY | Ph.D. | 1978 | Neuroanatomy | | The Salk Institute, LaJolla, CA | Resident Associate | 1982 | Neuropharmacology |
Professional Experience | 1982-1983 | Asst. Research Neuroscientist, Department of Neurosciences School of Medicine U. California, San Diego, La Jolla, California | | 1983-1988 | Asst. Professor, Department of Anatomy East Carolina U. Sch. Med. Greenville, NC
| | 1988-1993 | Assoc. Professor, Department of Anatomy & Cell Biology East Carolina U. Sch. Med. Greenville, NC | | 1993-1999 | Professor, Department of Anatomy & Cell Biology East Carolina U. Sch. Med. Greenville, NC | | 1999-present | Professor, Department of Neurosciences, MUSC, Charleston, SC
| | 2003-present | Associate Dean, College of Graduate Studies, MUSC, Charleston, SC
| | 2005-present | Professor, Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC |
Awards and Honors | 1978 | Member, New York Academy of Sciences | | 1978 | Member, Society for Neuroscience | | 1986 | Member, International Brain Research Organization | | 1986-1989 | Council member North Carolina Chapter of the Society for Neuroscience | | 1987 | INSERM Visiting Scientist Fellowship U. Grenoble, Grenoble France | | 1990-1991 | President, North Carolina Chapter of the Society for Neuroscience | | 1990-1996 | Member of Drug Abuse Biomedical Review Committee 3, NIDA | | 1990-1999 | Eastern Carolina Chapter of the Society for Neuroscience | | 1992 | Grass Traveling Scientist, New Orleans Chapter of the Society for Neuroscience | | 1999-2001 | SC Chapter of the Society for Neuroscience Board | | 2001-2005 | Member of NIH Biomedical Review IFCN-1 | | 2003-2005 | Chair of NIH Biomedical Review committee Neurobiology of Motivated Behavior (formerly IFCN-1) |
Recent Publications
Boger HA, Mannangatti P, Samuvel DJ, Saylor AJ, Bender TS, McGinty JF, Fortress AM, Zaman V, Huang P, Middaugh LD, Randall PK, Jayanthi LD, Rohrer B, Helke KL, Granholm AC & Ramamoorthy S. Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging. Genes, Brain, and Behavior 10(2):186-198, 2011. PMCID: PMC3026906 Hearing MC, Schwendt M & McGinty JF. Suppression of activity-regulated cytoskeleton-associated gene expression in the dorsal striatum attenuates extinction of cocaine-seeking. International Journal of Neuropsychopharmacology 14(6):784-795, 2011. PMCID: PMC3120104 Reichel CM, Schwendt M, McGinty JF, Olive MF & See RE. Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5. Neuropsychopharmacology 36(4):782-792, 2011. PMCID: PMC3052905 Shi X & McGinty JF. D1 and D2 dopamine receptors differentially mediate the activation of phosphoproteins in the striatum of amphetamine-sensitized rats. Psychopharmacology 214(3):653-663, 2011. PMCID: PMC3065836 Whitfield TW, Jr., Shi X, Sun WL & McGinty JF. The suppressive effect of an intra-prefrontal cortical infusion of BDNF on cocaine-seeking is Trk receptor and extracellular signal-regulated protein kinase mitogen-activated protein kinase dependent. Journal of Neuroscience 31(3):834-842, 2011. |
