Dr. John Woodward
Professor, Department of Neurosciences
Professor, Department of Psychiatry and Behavioral Sciences |
Visit Dr. Woodward's Lab Web site: at http://www.musc.edu/~woodward Research Interests Dr. Woodward’s lab is focused on defining the neural sites of action of alcohol and abused inhalants such as toluene and TCE. Alcohol and abused inhalants produce diverse effects on neuronal function by altering the function of different types of ion channels that regulate neuronal excitability. These include voltage dependent channels as well as those gated by neurotransmitters such as glutamate, Ach and ATP. Electrophysiological recording techniques are used to directly measure the function of both recombinant and native channels while site-directed mutagenesis is used to probe for discrete sites of action on the ion channel itself. Education | Texas A&M University, College Station, TX | B.S. | 1977 | Fish Biology/Physiology | | University of Washington, Seattle, WA | M.S. | 1979 | Fish Biology/Physiology | | University of Washington, Seattle, WA | Ph.D. | 1982 | Fish Biology/Physiology | | University of Texas, Austin, TX | Postdoctoral | 1989 | Neuropharmacology |
Professional Experience | 1982-1985 | Post-Doctoral Research Associate, Division of Pharmacology, University of Texas, Austin, TX | | 1986-1989 | Lecturer and Research Scientist, Division of Pharmacology and Institute for Neurological Sciences, University of Texas, Austin, TX | | 1989-1994 | Assistant Professor, Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA | | 1994-1999 | Associate Professor, Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA | | 1999-2001 | Professor, Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA | | 2001-present | Professor, Department of Neurosciences and Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC |
Awards and Honors | 1976 | Phi Kappa Phi National Honor Society | | 1976-1977 | University Undergraduate Research Fellow, Texas A&M University, College Station, TX | | 1981-1983 | University of Washington Egtvedt Scholarship for Academic Excellence, Seattle, WA | | 1985-1986 | National Research Service Award (NIMH), University of Texas at Austin, Austin, TX | | 1988-1989 | Nominated for Texas Excellence in Teaching Award | | 1991 | Outstanding Professor in Pharmacology/Toxicology, Virginia Commonwealth University, Richmond, VA | | 1998-2001 | NIAAA Study Section-AA1 Biomedical Research Review Subcommittee | | 1999 | Outstanding Professor in Pharmacology/Toxicology, Virginia Commonwealth University, Richmond, VA | | 2004-present | Chair, NIH Study Section (Neurotoxicology and Alcohol;NAL), Chair 2006-2008
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Recent Publications
Abernathy K, Chandler LJ & Woodward JJ. Alcohol and the prefrontal cortex. International Review of Neurobiology 91:289-320, 2010. Das A, McDowell M, Pava MJ, Smith JA, Reiter RJ, Woodward JJ, Varma AK, Ray SK & Banik NL. The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. Journal of Pineal Research 48(2):157-169, 2010. PMCID: PMC2862889 Beckley JT & Woodward JJ. The abused inhalant toluene differentially modulates excitatory and inhibitory synaptic transmission in deep-layer neurons of the medial prefrontal cortex. Neuropsychopharmacology 36(7):1531-1542, 2011. PMCID: PMC3096820 Mulholland PJ, Becker HC, Woodward JJ & Chandler LJ. Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses. Biological Psychiatry 69(7):625-632, 2011. PMCID: PMC3103782 Xu M, Smothers CT & Woodward JJ. Effects of ethanol on phosphorylation site mutants of recombinant N-methyl-d-aspartate receptors. Alcohol 45(4):373-380, 2011. PMCID: PMC3095724 |
