8/23/2012

David Weinshenker, Ph.D.
Associate Professor, Department of Human Genetics
Emory University School of Medicine

Mitrano DA, Schroeder JP, Smith Y, Cortright JJ, Bubula N, Vezina P, et al. Alpha-1 Adrenergic Receptors are Localized on Presynaptic Elements in the Nucleus Accumbens and Regulate Mesolimbic Dopamine Transmission. Neuropsychopharmacology. 2012;37(9):2161-72.

Schank JR, Ventura R, Puglisi-Allegra S, Alcaro A, Cole CD, Liles LC, et al. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology. 2006;31(10):2221-30.

Schroeder JP, Cooper DA, Schank JR, Lyle MA, Gaval-Cruz M, Ogbonmwan YE, et al. Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine beta-hydroxylase. Neuropsychopharmacology. 2010;35(12):2440-9.

9/13/2012

Barry Setlow, PhD
Associate Professor
Department of Psychiatry
McKnight Brain Institute
University of Florida College of Medicine

Mendez IA, Simon NW, Hart N, Mitchell MR, Nation JR, Wellman PJ & Setlow B. Self-administered cocaine causes long-lasting increases in impulsive choice in a delay discounting task. Behavioral Neuroscience 124(4):470-477, 2010. PMCID: 2976632

Simon NW, Gilbert RJ, Mayse JD, Bizon JL & Setlow B. Balancing risk and reward: a rat model of risky decision making. Neuropsychopharmacology 34(10):2208-2217, 2009. PMCID: 2726909

10/11/2012

Hendree Jones, PhD
Senior Research Psychologist
Substance Abuse Treatment Evaluations and Interventions Program
Research Triangle Institute

Jones HE, Kaltenbach K, Heil SH, Stine SM, Coyle MG, Arria AM, O'Grady KE, Selby P, Martin PR & Fischer G. Neonatal abstinence syndrome after methadone or buprenorphine exposure. New England Journal of Medicine 363(24):2320-2331, 2010. PMCID: 3073631

Jones HE, Martin PR, Heil SH, Kaltenbach K, Selby P, Coyle MG, Stine SM, O'Grady KE, Arria AM & Fischer G. Treatment of opioid-dependent pregnant women: clinical and research issues. Journal of Substance Abuse Treatment 35(3):245-259, 2008. PMCID: 2633026

Jones HE, O'Grady KE, Malfi D & Tuten M. Methadone maintenance vs. methadone taper during pregnancy: maternal and neonatal outcomes. American Journal on Addictions 17(5):372-386, 2008.

Maldve RE, Zhang TA, Ferrani-Kile K, Schreiber SS, Lippmann MJ, Snyder GL, Fienberg AA, Leslie SW, Gonzales RA & Morrisett RA. DARPP-32 and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens. Nature Neuroscience 5(7):641-648, 2002.

Jeanes ZM, Buske TR & Morrisett RA. In vivo chronic intermittent ethanol exposure reverses the polarity of synaptic plasticity in the nucleus accumbens shell. Journal of Pharmacology & Experimental Therapeutics 336(1):155-164, 2011. PMCID: 3014307

Bajo M, Roberto M, Madamba SG & Siggins GR. Neuroadaptation of GABAergic transmission in the central amygdala during chronic morphine treatment. Addiction Biology 16(4):551-564, 2011. PMCID: 3117063

Roberto M & Siggins GR. Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala. Proceedings of the National Academy of Sciences of the United States of America 103(25):9715-9720, 2006. PMCID: 1480472

Roberto M, Madamba SG, Stouffer DG, Parsons LH & Siggins GR. Increased GABA release in the central amygdala of ethanol-dependent rats. Journal of Neuroscience 24(45):10159-10166, 2004.

Nie Z, Schweitzer P, Roberts AJ, Madamba SG, Moore SD & Siggins GR. Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors. Science 303(5663):1512-1514, 2004

Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC & Cha JH. Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. Journal of Neuroscience 30(35):11735-11744, 2010. PMCID: 2943400

Vassoler FM, White SL, Schmidt HD, Sadri-Vakili G & Pierce RC. Epigenetic inheritance of a cocaine-resistance phenotype. Nature Neuroscience 16(1):42-47, 2013. PMCID: 3531046

Marisa Roberto, Ph.D.
Associate Professor
The Scripps Research Institute

Cruz MT, Herman MA, Kallupi M, et al (2012). Nociceptin/orphanin FQ blockade of corticotropin-releasing factor-induced gamma-aminobutyric acid release in central amygdala is enhanced after chronic ethanol exposure. Biol Psychiatry 71: 666-676.

Roberto M, Cruz MT, Gilpin NW, et al (2010). Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence. Biol Psychiatry 67: 831-83

Brevig H N and Baghdoyan H A (2010) Neurotransmitters and Neuromodulators Regulating Sleep and Wakefulness. In: Koob G.F., Le Moal M. and Thompson R.F. (eds.) Encyclopedia of Behavioral Neuroscience, volume 3, pp. 456–463. Oxford: Academic Press.

Carter CS & Porges SW (2013). The biochemistry of love: an oxytocin hypothesis. EMBO Rep 14: 12-16.

Van Zessen R, Phillips JL, Budygin EA, Stuber GD. Activation of VTA GABA neurons disrupts reward consumption. Neuron. 2012;73(6):1184-94.

Stuber GD, Sparta DR, Stamatakis AM, van Leeuwen WA, Hardjoprajitno JE, Cho S, et al. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. 2011;475(7356):377-80.

Lawrence AJ, Cowen MS, Yang HJ, Chen F, Oldfield B. The orexin system regulates alcohol-seeking in rats. Br J Pharmacol. 2006;148(6):752-9.

Jupp B, Krstew E, Dezsi G, Lawrence AJ. Discrete cue-conditioned alcohol-seeking after protracted abstinence: pattern of neural activation and involvement of orexin(1) receptors. Br J Pharmacol. 2011;162(4):880-9.

Brown RM, Lawrence AJ. Ascending orexinergic pathways and alcohol-seeking. Curr Opin Neurobiol. 2013.

Brown RM, Yon-Seng Khoo S, Lawrence AJ. Central orexin (hypocretin) 2 receptor antagonism reduces ethanol self-administration, but not cue-conditioned ethanol-seeking, in ethanol-preferring rats. Int J Neuropsychopharmacol. 2013:1-13.