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CDAP > Center for Drug and Alcohol Programs Clinical Trials
Center for Drug and Alcohol Programs Clinical Trials

We are currently recruiting participants for the following clinical and non-treatment studies. Each study has age and other requirements and certain clinical exclusions. One advantage of participation is that subjects receive treatment that is free of charge and confidential.  Some studies even provide payment to participants. 

Current Studies
(please select the appropriate heading to learn more about the treatment or non-treatment studies) 
 - Alcohol Treatment Studies
 - Cocaine &Methamphetamine Treatment Studies 
 -
  Non-Treatment Studies   

If you are interested in any of these studies, please call the telephone number listed for that study. 

 More information on Clinical Trials at MUSC 

                        ALCOHOL TREATMENT STUDIES                      

Clinical Trial Name: Adolescent Alcohol Treatment
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Deborah Deas, MD, MPH
Project Coordinator: Natalie Johnson, MA
Contact Person: Natalie Johnson, MA
Contact Number: 843-876-5070
Study Medications: Naltrexone or Placebo
Therapy: 12 weeks, after twelve week treatment phase, participants will return to the site at 6, 9, and 12 months for follow-up assessments.
                                          Age Requirement: 15-25

Clinical Trial Name: An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Raymond Anton, MD
Project Coordinator: Pat Latham, RN, PhD, CS or Konstantin E. Voronin, MD, PhD
Contact Person: Pat Latham, RN, PhD, CS or Konstantin E. Voronin, MD, PhD
Contact Number: 843-792-2727 or 843-792-1230
Study Medications: Naltrexone/Placebo, Naltrexone/Aripiprazole, or Placebo/Placebo
Therapy: Individual Medical Management Sessions over 16 weeks
Age Requirement: 18-70

Clinical Trial Name: Genetic and brain mechanisms of naltrexone’s treatment 
  efficacy for alcoholism
  Funding Source: NIAAA
  Principal Investigator: Raymond Anton, MD
  Project Coordinator: Konstantin E. Voronin, MD, PhD
  Contact Person: Konstantin E. Voronin, MD, PhD
  Contact Number: 843-792-2727
  Study Medications: Naltrexone/Placebo
  Therapy: Individual Medical Management Sessions over 16 weeks
  Age Requirement: 18-70 

     COCAINE & METHAMPHETAMINE TREATMENT STUDIES     

Clinical Trial Name: Modafinil and CBT for Cocaine Addiction
Funding Source: National Institute on Drug Abuse (NIDA)
Principal Investigator: Robert Malcolm, MD
Research Assistant: Kelley Barnes, BA
Contact Person: Melissa Corley, MA
Contact Number: 843-792-2727
Study Medications: Modafinil or Placebo
Therapy: 8 weekly sessions of Cognitive Behavioral Therapy (CBT)
Frequency of visits: Tri-weekly visits, 1-2 week screening period, 8 week treatment period and 2
                                         
follow-up visits.
                                        
  Age Requirement: 18-65  

NON-TREATMENT STUDIES 

CDAP also recruits participants for non-treatment laboratory studies. These studies help us learn about basic biological, genetic or behavioral aspects of alcohol use and abuse. Many of these studies provide payment to participants.

Study Name: Clinical Circuitry Underlying Methamphetamine Cue Craving and Cue Extinction
Funding Source: National Institute on Drug Abuse (NIDA)
Principal Investigator: Robert Malcolm, MD
Project Coordinator: Kristi Huebner, MPH
Contact Person: Melissa Corley, MA
Contact Number: 843-792-2727
Study Medications: None
Therapy: None
Age Requirement: 18-65

Study Name: Effects on Medication Treatment on Cue-Induced Brain Activation in Alcoholics
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Hugh Myrick, MD
Project Coordinator: Scott Henderson, BA
Contact Person: Scott Henderson, BA
Contact Number: 843-792-5560
Study Medications: Aripiprazole/Chantix/Placebo
                                         Therapy: None
                                         Age Requirement: 21-65

Study Name: Evaluating the Genetic Variability of Naltrexone Response
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Raymond Anton, MD
Project Coordinators: Konstantin Voronin, MD, PhD or Abraham Tiffany, BS
Contact Person: Abraham Tiffany, BS
Contact Number: 843-792-9955
Study Medications: Naltrexone/Placebo
Therapy: None
Age Requirement: 21-65



Study Name: Personality and Alcohol Preference
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Suzanne Thomas, PhD
Research Assistant: Kathryn Morrow, BS
Contact Person: Kathryn Morrow, BS
Contact Number: 843-792-5811
Study Medications: None
                                         Therapy: None
                                         Age Requirement: 21-65

 
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"I felt at all times that the staff I encountered were very interested in helping me. I never felt like a 'number.' "-CEL

" I did not feel judged or less of a person because of my alcohol issues. It has been a very positive experience...I also now realize this is a forever problem that I have to address on a daily basis."-Bobby

"This was an excellent experience. I learned a lot about alcohol dependence, coping strategies and other health related issues as they involve alcohol consumption. Most importantly my personal and family life have improved dramatically. Thank you, thank you, thank you!" -James