We are currently recruiting participants for the following clinical and non-treatment studies. Each study has age and other requirements and certain clinical exclusions. One advantage of participation is that subjects receive treatment that is free of charge and confidential.  Some studies even provide payment to participants. 

Current Studies
(please select the appropriate heading to learn more about the treatment or non-treatment studies) 
 - Alcohol Treatment Studies
 - Cocaine &Methamphetamine Treatment Studies 
 -  Non-Treatment Studies

If you are interested in any of these studies, please call the telephone number listed for that study. 

 More information on Clinical Trials at MUSC 

Clinical Trial Name: Adolescent Alcohol Treatment
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Deborah Deas, MD, MPH
Project Coordinator: Natalie Johnson, MA
Contact Person: Natalie Johnson, MA
Contact Number: 843-876-5070
Study Medications: Naltrexone or Placebo
Therapy: 12 weeks, after twelve week treatment phase, participants will return to the site at 6, 9, and 12 months for follow-up assessments.
                                          Age Requirement: 15-25

Clinical Trial Name: An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence
Funding Source: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Raymond Anton, MD
Project Coordinator: Pat Latham, RN, PhD, CS or Alicia Baros, PhD
Contact Person: Pat Latham, RN, PhD, CS or Alicia Baros, PhD
Contact Number: 843-792-2727 or 843-792-1230 or 843-792-0073
Study Medications: Naltrexone/Placebo, Naltrexone/Aripiprazole, or Placebo/Placebo
Therapy: Individual Medical Management Sessions over 16 weeks
Age Requirement: 18-70

Clinical Trial Name: A Phase 2 Study of LY2196044 Compared with Placebo   
  in the Treatment of Alcohol Dependence
  Funding Source: Eli Lilly and Company
  Principal Investigator: Raymond Anton, MD
  Project Coordinator: Pat Latham, RN, PhD, CS or Alicia Baros, PhD
  Contact Person: Pat Latham, RN, PhD, CS or Alicia Baros, PhD
  Contact Number: 843-792-2727 or 843-792-1230 or 843-792-0073
  Study Medications: LY2196044/Placebo
  Therapy: Individual Medical Management Sessions over 16 weeks
  Age Requirement: 21-65

  Clinical Trial Name: Genetic and brain mechanisms of naltrexone’s treatment 
  efficacy for alcoholism
  Funding Source: NIAAA
  Principal Investigator: Raymond Anton, MD
  Project Coordinator: Konstantin E. Voronin, MD, Ph.D
  Contact Person: Konstantin E. Voronin, MD, Ph.D
  Contact Number: 843-792-2727
  Study Medications: Naltrexone/Placebo
  Therapy: Individual Medical Management Sessions over 16 weeks
  Age Requirement: 18-70

  Clinical Trial Name: A Phase II Multicenter, Randomized, Double-Blind, Two-
  Stage Clinical Trial to Evaluate the Efficacy and
  Safety of MK-0594 in Patients with Alcohol Dependence.
  Funding Source: Merck & Co., Inc
  Principal Investigator: Raymond Anton, MD
  Project Coordinator: Konstantin E. Voronin, MD, Ph.D
  Contact Person: Konstantin E. Voronin, MD, Ph.D
  Contact Number: 843-792-2727
  Study Medications: MK-0594/Placebo
  Therapy: Individual Medical Management Sessions over 12 weeks
  Age Requirement: at least 21 years old

Clinical Trial Name: Modafinil and CBT for Cocaine Addiction
Funding Source: National Institute on Drug Abuse (NIDA)
Principal Investigator: Robert Malcolm, MD
Research Assistant: Kelley Barnes, BA
Contact Person: Melissa Corley, MA
Contact Number: 843-792-2727
Study Medications: Modafinil or Placebo
Therapy: 8 weekly sessions of Cognitive Behavioral Therapy (CBT)
Frequency of visits: Tri-weekly visits, 1-2 week screening period, 8 week treatment period and 2
                                          follow-up visits.
                                          Age Requirement: 18-65

 Clinical Trial Name: A Controlled Trial of N-Acetylcysteine for the Treatment of
 Cocaine Dependence
 Funding Source: National Institute on Drug Abuse (NIDA)
 Principal Investigator: Robert Malcolm, MD
 Project Coordinator: Kristi Huebner, MPH
 Contact Person: Melissa Corley, MA
 Contact Number: 843-792-2727
 Study Medications: N-Acetylcysteine or Placebo
 Therapy: Cognitive Behavioral Therapy (CBT)
 Frequency of visits: Tri-weekly visits
 Age Requirement: 18-65