Medical University  |  MUSC Hospital  |  College of Medicine  |  Directory


ART left image

About the Program




MUSC Program for Thrombosis and Hemostasis Care
MUSC Anticoagulation and Bleeding Management Service

Inpatient Consult Service

Inpatient Consult Simon Pager: 1-7888 (Anticoag & Bleeding Mgmt)

Outpatient Referral Line: (843) 792-9200

Dr. Charles S Greenberg, (843) 991-8785,
Dr. Ming Lim, pager 1-4004,
Caroline Vaughn, RN, Nurse Coordinator (843) 792-2348,

Attending physicians on this service have significant clinical and research interests in the area of hemostasis and thrombosis and are available on a 24-hour basis. The close integration of the MUSC Coagulation Consult Service with the Clinical Coagulation Laboratory allows us to provide a number of unique services.


The Medical University of South Carolina has initiated a multidisciplinary approach for the management of thrombosis and bleeding. Physicians, pharmacists, nurses and scientists collaborate to provide exceptional care for patients suffering from bleeding and blood clotting problems. A comprehensive set of educational videos, podcasts, conferences and written materials are available to assist clinicians and patients in learning about these complex disorders.

Please see our ANTICOAGULATION webpage on the MUSC Intranet:


The primary mission of the Anticoagulation and Bleeding Management Service is to assist in the diagnosis, treatment, and prevention of bleeding or blood clotting problems that produce pain and suffering in our patients. We are committed to providing excellent care for patients with complex blood and bone marrow disorders in our academic medical center by using evidence-based medicine and state-of-the-art diagnostics, while striving to make new scientific discoveries that will continue to improve the care of these disorders in the future. 

The program offers advice regarding:

identification of the cause of recurrent thrombosis,
the duration and intensity of anticoagulation,
identification of the etiology of inherited or acquired bleeding disorders,
the treatment of bleeding disorders,
recommendations on using newly-approved anticoagulants
anemias, leukopenias, platelet disorders, and other non-malignant disorders of the bone marrow

The Adult Hematology Outpatient Clinic is located on the second floor of Ashley River Tower.  We are dedicated to the diagnosis and treatment of complex bleeding and blood clotting problems and non-malignant blood and bone marrow disorders.


The School of Pharmacy at MUSC offers inpatient consultative advice regarding proper dosing and monitoring of medications used to treat bleeding and blood clotting disorders in collaboration with the primary physician and consulting hematologist.

Pharmacotherapy Clinic

Experienced pharmacists specializing in warfarin management provide care for outpatients needing to have anticoagulation monitored and adjusted, in collaboration with the primary physician. Patients are referred to the clinic by physicians and can be cared for at several different location throughout the Charleston area.

A program is also available to allow selected patients to self-monitor therapy at home in collaboration with our hematologists.


The clinical laboratory has the capacity to provide diagnostic testing to define the cause of bleeding and thrombosis. Assays utilizing plasma, platelets or patient DNA are available to provide state-of-the-art evaluation. The laboratory is also prepared to assist in the monitoring of anticoagulation therapy with specialized testing to measure level of heparin, low molecular weight heparin, and antiplatelet therapies.

Most recently, MUSC was the first SC hospital to implement the ROTEM® whole blood coagulation testing device to rapidly diagnose and treat patients with active bleeding.  It is extremely useful in determining appropriate blood product use to improve outcomes for our patients.


The interventional radiologists are experts in performing thrombolytic therapy for arterial and venous thrombosis. In addition, they can provide protection from pulmonary emboli by placing removable inferior vena cava filters in patients that cannot receive full-dose anticoagulation therapy.


Vascular surgeons skilled in the diagnosis and treatment of both arterial and venous disease are available for consultation. The vascular lab utilizes venous duplex scanning to assist in the diagnosis of venous disease. The vascular laboratory provides a wide range of additional services including carotid duplex, arterial duplex, aortic duplex, renal artery duplex and additional state-of-the-art noninvasive techniques.


The Blood Bank at MUSC can support the bleeding patient by providing the necessary plasma, cryoprecipitate, recombinant proteins, platelets and red blood cells that are needed to manage life-threatening bleeding problems.


A wide variety of cardiovascular disorders can promote arterial thrombosis. The MUSC Cardiology and Cardiovascular Surgery can assist in identifying and treating these disorders using state-of-the-art diagnostic testing, noninvasive and surgical techniques.

Coagulation Consult Service