Department of Ophthalmology

Peer-Reviewed Publications 2007-2012

McKee TD, Lewis MR, and Kono M. Engineering a “steric doorstop” in rhodopsin: converting an inverse agonist to an agonist. Biochemistry 46:12248-12252, 2007; PMID: 17918963.

Kono M, Goletz PW, and Crouch RK. 11-cis and all-trans retinols can activate rod opsin: Rational design of the visual cycle. Biochemistry 47:7567-7571, 2008; PMCID: PMC2561911.

Park PS-H, Sapra KT, Jastrzebska B, Maeda T, Maeda A, Pulawski W, Kono M, Lem J, Crouch RK, Filipek S, Müller DJ, and Palczewski K. Modulation of molecular interactions and function by rhodopsin palmitylation. Biochemistry 48:4294-4304, 2009; PMCID: PMC2710298.

Ala-Laurila, P, Cornwall MC, Crouch RK, and Kono M. The action of 11-cis-retinol on cone opsins and intact cone photoreceptors. J Biol Chem 284:16492-16500, 2009; PMCID: PMC2713570.

Kono M, and Crouch RK. In vitro assays of rod and cone opsin activity: Retinoid analogs as agonists and inverse agonists. Methods Mol Biol 652:85-94, 2010; PMID: 20552423.

Fan J, Crouch RK, and Kono M. Light prevents exogenous 11-cis retinal from maintaining cone photoreceptors in chromophore-deficient mice. Invest Ophthalmol Vis Sci 52:2412-2416, 2011; PMCID: PMC3081252.

Kono M, and Crouch RK. Probing human red cone opsin activity with retinal analogues. J Nat Prod 74:391-394, 2011; PMCID: PMC3064742.

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