
ABBREVIATED CV OF Dr. Koutalos PEER-REVIEWED PUBLICATIONS 2006-2011 GRANT SUPPORT 2006-2011 LABORATORY PERSONNEL Principal Investigator, Yiannis Koutalos, Ph.D. Research Tech III,Chunhe Chen, Ph.D. Research Tech I, Nicholas Boyer, B.S. Undergrad. Student, Lee Adler Undergrad. Student, Jeffrey Bertel Undergrad. Student, Colleen Sheridan Undergrad. Student,Alex Verderber
PICTURES OF LABORATORY ACTIVITIES http://academicdepartments.musc.edu/stormeye_research/koutalos/ SUMMARY OF LABORATORY RESEARCH My laboratory studies the physiology of photoreceptor cells, the sensory neurons that convert light into an electrical signal. The detection of light by these cells involves the formation of waste byproducts that need to be eliminated. I am interested in the generation and clearance of these byproducts, as well as in their effects on cell function. Impairment of waste removal underlies a variety of retinal diseases, including age-related macular degeneration, Stargardt disease, and some forms of retinitis pigmentosa. We use fluorescence imaging to visualize and measure the formation, removal, and the deleterious effects of these toxic byproducts in living photoreceptor cells in real time.
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