Division of cardiology

Terrence O'Brien, M.D.,MS, FACC

Professor of Medicine

Dr. O’Brien is board certified in Cardiovascular Medicine and Internal Medicine.  He is a graduate of the University of California, San Diego School of Medicine. His undergraduate degree is in Chemistry and he has a Master’s Degree in Biological Sciences, both at Stanford University. Dr. O’Brien did his Internal Medicine Residency at Southwestern Medical Center in Dallas (Parkland Hospital), a clinical Cardiology Fellowship at the University of California, San Diego where he also did a research Cardiology Fellowship in Molecular Cardiology as a Bugher Fellow.  Dr. O’Brien is currently an Associate Professor of Medicine and Cell Biology and Anatomy at the Medical University of South Carolina where he has been since 1993. 

Dr. O’Brien’s clinical interests include all aspects of inpatient and outpatient general cardiology. He sees scheduled patients at MUSC downtown as well as at the MUSC Outreach Cardiology Clinic in East Cooper, where he is the Medical Director.

Dr. O’Brien also serves as the Director of the Echocardiography Laboratory at the Ralph H. Johnson Department of Veteran's Affairs Medical Center in Charleston and is the Director of Clinical Cardiovascular Research at the Medical University of South Carolina. 

Dr. O’Brien's research career has involved both basic laboratory research examining the mechanisms of heart hypertrophy and failure as well as participation in human clinical trials evaluating new medications and diagnostic techniques in patients with various forms of heart failure.

Dr. O’Brien is the author of over 45 peer reviewed publications.  He is a member of a number of professional societies including the American Society of Echocardiography, the American Heart Association, the American College of Cardiology, the Heart Failure Society of America, the International Society for Heart Research, and the Southern Society for Clinical Investigation. Dr. O’Brien’s research has been supported by grants from the National Heart, Lung and Blood Institute, the Department of Veterans Affairs, the American Heart Association, the Medical University of South Carolina and numerous other sponsors. 

PDF Icon Dr. Terrance O'Brien's Curriculum Vitae (PDF Format)*

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 More on Dr. O'Brien

Dr. O'Brien

Terrence O'Brien, M.D.

Dr. O'Brien's Clinical Interests

General Cardiology
Congestive heart failure
Valvular heart disease
Preventative and diagnostic cardiology

Request an Appointment with Dr. O'Brien

 New patients may call 
    MUSC Health Connection 
    at 1-843-792-1414

 Online Request

Selected Publications

View a partial list of Dr. O'Brien's publications through the National Library of Medicine's PubMed online database.
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