Department of radiology and Radiological Science

Neuroradiology


Faculty | Equipment | Research


Faculty

Associate Professcor
Diagnostic Neuroradiology Chief
Fellowship Program Director
  
Professor
Director, Interventional Spine Radiology
   
    
Assistant Professor
  
Seth T. Stalcup, M.D.
Assistant Professor
   
Assistant Professor
   
Brandi Aquino, PA-C
Physician Assistant
    
Michael U. Antonucci, M.D.
Assistant Professor
  

Equipment and Resources

The Medical University of South Carolina has state-of-the-art equipment, including three 3T MR scanners (2 clinical and 1 research, all on campus), four 1.5T MR scanners (3 on campus, 1 in Mount Pleasant) and eight CT scanners (7 on campus, 1 in Mount Pleasant), including two dual-source CT scanners. The neuroradiology reading room will be renovated and expanded by July 2015 to accommodate seven PACS workstations.

Research


Head and Neck Cancer | Brain Tumors | Cerebrovascular | Alzheimer's Disease | CNS | Trauma | Spine | CT | MRI | TMS


Head and Neck Cancer

Past Research

  • Feasibility and potential value of perfusion CT
  • Predictive role of CT for residual nodal disease following (chemo) radiation
  • Correlation of PET-CT and perfusion CT
  • Refining and optimizing PET-CT studies

Current Projects

  • Predictive role of perfusion CT
  • Accuracy of PET-CT for oral and oropharyngeal cancer recurrence (Dr. Spampinato)
  • Thyroid cancer risks during CT perfusion studies of the neck (Dr. Spampinato with Dr. Huda)
  • Establishing criteria for extracapsular spread of metastatic nodal disease (Dr. Matheus)
  • Predictive role of extracpsular spread - possible staging adjustment (Dr. Matheus)
  • Rapamycin for oral and oropharyngeal cancer

Brain Tumors

Past Research

  • Diffusion MR imaging for differentiation of brain tumors
  • Predictive role of perfusion MRI
  • Comparison of various MRI contrast agents for intracranial disease processes

Current Projects

  • Diffusion kurtosis imaging (DKI) for glial brain neoplasms (Dr. Spampinato)
  • Use of advanced MRI for evaluation and prediction of treatment response in recurrent glioblastoma multiform (GBM) (Dr. Spampinato)
  • Application of susceptibility-weighted imaging (SWI) for diagnosis and follow-up of brain tumors (Dr. Spampinato)
  • Assessment of treated gliomas (Dr. Matheus)

Cerebrovascular

Past Research

  • Posterior reversibile encephalopathy syndrome
  • Multicentric study on patients with intracranial vascular stenosis
  • MR angiograms for embolized cerebral aneurysms
  • Comparison of patient radiation doses with CTA and DSA
  • Effect of chronic transfusion therapy on progression of neurovascular pathology in pediatric patients with sickle cell anemia

Current Projects

  • Human cerebral vascular autoregulation and venous outflow in response to microgravity-induced cephalad fluid redistribution (NASA) (Dr. Roberts)
  • Multicentric study on treatment of patients with intracranial vascular stenosis (SAMMPRIS, NIH)
  • Stroke patterns and causative mechanisms in patients with symptomatic intracranial atherosclerossis (Dr. Matheus)
  • Assessment of collateral arterial circulationi in stroke patients using CTA data (Dr. Matheus)
  • Phase III randomized clinical trial to compare standard therapy (erythrocyte transfusions) with alternative therapy (hydroxyura) in pediatric subjects with sickle cell disease (TWiTCH, NIH) (Dr. Roberts, consultant)
  • Intracranial vascular wall imaging in patients with brain infarcts and intracranial atrterial stenoses (CHIASM)

Alzheimer's Disease

Past Research

  • Apolipoprotein E and gray matter volume loss inpatients with mild cognitive impairment and Alzheimer's Disease

Current Projects

  • Voxel-based morphometry for evaluation of differences between genders (Dr. Spampinato)
  • Comparison with clinical tests in Alzheimer's Disease and mild cognitive impairment (Dr. Spampinato)

Genetic CNS Disorders

Past Research

  • Imaging characteristics of Joubert syndrome - absent commissure of the superior cerebellar peduncles

Current Project

  • Translational approach for the study of Snyder-Robinson syndrome, an X-linked developmetnal disorder (Dr. Matheus)

Trauma

Current Project

  • The Injury and Traumatic strees (INTRuST) Consortium Neuroimaging Acquisition and Archival (Dr. Roberts, consultant)

Spine

Past Research

  • Optimization of spianl MRA
    Perfusion CT of the spinal cord
  • Spinal cord perfusion CT changes with radiation treatment of the head and neck
  • Evaluation and optimization of interventional spine procedures
  • Animal model of spinal injury

Current Project

  • Comparison of radiation only vs. radiation + vertebroplasty for spinal metastatic tumors (Dr. Bartynski)

CT

Past Research

  • Portable head CT imaging

Current Projects

  • Detail detection on head CT (Dr. Spampinato with Dr. Huda)
  • Estimating organ doses at head and neck CT (Dr. Spampinato with Dr. Huda)

MRI

Past Research

  • Comparison of different ways of performing brain perfusion MRI
  • Human cerebral cortex plasticity in response to lower limb immobilization
  • Reproducibility of fMRI BOLD activation correlated with cortical excitability human cerebral cortex plasticity in response to long-term bedrest as an analog to microgravity

Current Projects

  • Evaluation of brain radiation effects (Dr. Spampinato)
  • Evaluation of DKI information in patients with multiple sclerosis (Dr. Spampinato)
  • Use of DKI for tractography - mapping of cerebral white matter tracts (Dr. Tabesh)

Transcranial Magnetic Stimulation

Current Project

  • Interleaved TMS and fMRI for mapping of language networks (Dr. Roberts)
 
 
 

© Medical University of South Carolina | 171 Ashley Avenue, Charleston, SC 29425